Energy and ATP
- The chemical energy stored in glucose must be released by all cells through a series of enzyme-controlled reactions called respiration.
- The energy released from the breakdown of glucose is used to generate ATP.
- The energy transferred by ATP can be used for cellular activities such as
- muscle cell contraction,
- cell division,
- protein synthesis
- transmission of nerve impulses.
Aerobic Respiration
- Glucose is broken down to two molecules of pyruvate, releasing enough energy to yield two molecules of ATP.
- Further breakdown depends upon the presence/absence of oxygen.
If oxygen is present, aerobic respiration takes place, and each pyruvate is broken down to carbon dioxide and water, releasing enough energy to yield a large number of ATP molecules.
Fermentation Pathway
- In the absence of oxygen, the fermentation pathway takes place.

- In animal cells, the pyruvate molecules are converted to lactate and in plant and yeast cells they are converted to carbon dioxide and ethanol.
- The breakdown of each glucose molecule via the fermentation pathway yields only the initial two molecules of ATP.
Location of Respiration

- Respiration begins in the cytoplasm.
- The process of fermentation is completed in the cytoplasm whereas aerobic respiration is completed in the mitochondria.
- The higher the energy requirement of a cell the greater the number of mitochondria present in that cell.
Respirometer
- A respirometer measures the rate of respiration in organisms.